טוען...
The Role of miR-18b in MDM2-p53 Pathway Signaling and Melanoma Progression
BACKGROUND: Although p53 is inactivated by point mutations in many tumors, melanomas infrequently harbor mutations in the p53 gene. Here we investigate the biological role of microRNA-18b (miR-18b) in melanoma by targeting the MDM2-p53 pathway. METHODS: Expression of miR-18b was examined in nevi (n...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601951/ https://ncbi.nlm.nih.gov/pubmed/23365201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt003 |
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