BPTF transduces MITF-driven prosurvival signals in melanoma cells

Microphthalmia-associated transcription factor (MITF) plays a critical and complex role in melanocyte transformation. Although several downstream targets of MITF action have been identified, the precise mechanisms by which MITF promotes melanocytic tumor progression are incompletely understood. Rece...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Dar, Altaf A., Majid, Shahana, Bezrookove, Vladimir, Phan, Binh, Ursu, Sarah, Nosrati, Mehdi, De Semir, David, Sagebiel, Richard W., Miller, James R., Debs, Robert, Cleaver, James E., Kashani-Sabet, Mohammed
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896689/
https://ncbi.nlm.nih.gov/pubmed/27185926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606027113
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