Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity

We have shown in rats that sodium salicylate (SS), which inhibits IkBa kinase B (IKKB), prevents hepatic and peripheral insulin resistance caused by short-term (7 h) i.v. administration of Intralipid and heparin (IH). We wished to further determine whether this beneficial effect of SS persisted afte...

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Detalhes bibliográficos
Main Authors: Pereira, Sandra, Yu, Wen Qin, Frigolet, María E, Beaudry, Jacqueline L, Shpilberg, Yaniv, Park, Edward, Dirlea, Cristina, Nyomba, B L Grégoire, Riddell, Michael C, Fantus, I George, Giacca, Adria
Formato: Artigo
Idioma:Inglês
Publicado em: BioScientifica 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601809/
https://ncbi.nlm.nih.gov/pubmed/23328071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-12-0214
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