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Attenuation of Free Fatty Acid (FFA)-Induced Skeletal Muscle Cell Insulin Resistance by Resveratrol is Linked to Activation of AMPK and Inhibition of mTOR and p70 S6K

Insulin resistance, a main characteristic of type 2 diabetes mellitus (T2DM), is linked to obesity and excessive levels of plasma free fatty acids (FFA). Studies indicated that significantly elevated levels of FFAs lead to skeletal muscle insulin resistance, by dysregulating the steps in the insulin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Den Hartogh, Danja J., Vlavcheski, Filip, Giacca, Adria, Tsiani, Evangelia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404286/
https://ncbi.nlm.nih.gov/pubmed/32664532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21144900
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