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Mechanism of free fatty acid-induced insulin resistance in humans.

To examine the mechanism by which lipids cause insulin resistance in humans, skeletal muscle glycogen and glucose-6-phosphate concentrations were measured every 15 min by simultaneous 13C and 31P nuclear magnetic resonance spectroscopy in nine healthy subjects in the presence of low (0.18 +/- 0.02 m...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Roden, M, Price, T B, Perseghin, G, Petersen, K F, Rothman, D L, Cline, G W, Shulman, G I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675698/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118742
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