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Comparable dimerization found in wildtype and familial Alzheimer’s disease amyloid precursor protein mutants

Alzheimer’s disease (AD) is a progressive and fatal neurodegenerative disorder marked by memory impairment and cognitive deficits. A major component of AD pathology is the accumulation of amyloid plaques in the brain, which are comprised of amyloid beta (Aβ) peptides derived from the amyloidogenic p...

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Detalhes bibliográficos
Main Authors: So, Pauline PL, Khodr, Christina E, Chen, Ci-Di, Abraham, Carmela R
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601467/
https://ncbi.nlm.nih.gov/pubmed/23515184
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