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Myeloid-derived suppressor cells and the efficacy of CD8(+) T-cell immunotherapy
Myeloid-derived suppressor cells (MDSCs) promote immune evasion, a key feature of oncogenesis. The restoration of immunosurveillance by immunomodulatory antibodies improves the survival of a subset of cancer patients. Preclinical studies suggest that the ablation of monocytic MDSCs may be a useful a...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601158/ https://ncbi.nlm.nih.gov/pubmed/23525353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22764 |
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