IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation

The susceptibility of macrophages to HIV-1 infection is modulated during monocyte differentiation. IL-27 is an anti-HIV cytokine that also modulates monocyte activation. In this study, we present new evidence that IL-27 promotes monocyte differentiation into macrophages that are nonpermissive for HI...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Dai, Lue, Lidie, Kristy B., Chen, Qian, Adelsberger, Joseph W., Zheng, Xin, Huang, DaWei, Yang, Jun, Lempicki, Richard A., Rehman, Tauseef, Dewar, Robin L., Wang, Yanmei, Hornung, Ronald L., Canizales, Kelsey A., Lockett, Stephen J., Lane, H. Clifford, Imamichi, Tomozumi
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600911/
https://ncbi.nlm.nih.gov/pubmed/23460728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120572
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares