Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.

IL-27, a member of the IL-12 family of cytokines, plays an important and diverse role in the function of the immune system. Whilst generally recognized as an anti-inflammatory cytokine, in addition IL-27 has been found to have broad anti-viral effects. Recently, IL-27 has been shown to be a potent i...

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Main Authors: Qian Chen, Sanjay Swaminathan, De Yang, Lue Dai, Hongyan Sui, Jun Yang, Ronald L Hornung, Yanmei Wang, Da Wei Huang, Xiaojun Hu, Richard A Lempicki, Tomozumi Imamichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3604098?pdf=render
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