Insulin gene expression in nonexpressing cells appears to be regulated by multiple distinct negative-acting control elements.
Selective transcription of the insulin gene in pancreatic beta cells is regulated by its enhancer, located between nucleotides -340 and -91 relative to the transcription start site. Transcription from the enhancer is controlled by both positive- and negative-acting cellular factors. Cell-type-specif...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1991
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2017182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.5.2881-2886.1991 |
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