Insulin gene expression in nonexpressing cells appears to be regulated by multiple distinct negative-acting control elements.

Selective transcription of the insulin gene in pancreatic beta cells is regulated by its enhancer, located between nucleotides -340 and -91 relative to the transcription start site. Transcription from the enhancer is controlled by both positive- and negative-acting cellular factors. Cell-type-specif...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Cordle, S R, Whelan, J, Henderson, E, Masuoka, H, Weil, P A, Stein, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2017182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.5.2881-2886.1991
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