Insulin gene expression in nonexpressing cells appears to be regulated by multiple distinct negative-acting control elements.

Ítems similars

• Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence.
  per: Whelan, J, et al.
  Publicat: (1990)
• Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.
  per: Cordle, S R, et al.
  Publicat: (1991)
• Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements.
  per: Whelan, J, et al.
  Publicat: (1989)
• Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression.
  per: Robinson, G L, et al.
  Publicat: (1994)
• c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of control.
  per: Henderson, E, et al.
  Publicat: (1994)