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Protoporphyrin IX/Cobyrinate Derived Hybrids – Novel Activators of Soluble Guanylyl Cyclase

A new cobyrinate/protoporphyrin IX molecular hybrids were prepared via CuAAC reaction. The synthesis involved selective preparation of cobyrinate and PpIX derived building blocks possessing respectively terminal alkyne and azide moieties followed by the CuOAc catalyzed cycloaddition reaction. Synthe...

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Main Authors: Chromiński, Mikołaj, Proinsias, Keith ó, Martin, Emil, Gryko, Dorota
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600653/
https://ncbi.nlm.nih.gov/pubmed/23519483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201201303
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