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Vitamin B(12) Derivatives as Activators of Soluble Guanylyl Cyclase

Various newly prepared and previously known vitamin B(12) derivatives have been studied as potential soluble guanylyl cyclase (sGC) activators. All compounds tested were found to activate the sGC enzyme, although to differing extents. The best results were obtained with the derivatives synthesized f...

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Detalhes bibliográficos
Main Authors: Proinsias, Keith ó, Gryko, Daniel T., Hisaeda, Yoshio, Martin, Emil, Sessler, Jonathan L., Gryko, Dorota
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671888/
https://ncbi.nlm.nih.gov/pubmed/22991977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3006959
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