Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acid β-Oxidative Genes: Synergistic Roles of L-FABP and Glucose

While TOFA (acetyl CoA carboxylase inhibitor) and C75 (fatty acid synthase inhibitor) prevent lipid accumulation by inhibiting fatty acid synthesis, the mechanism of action is not simply accounted for by inhibition of the enzymes alone. Liver fatty acid binding protein (L-FABP), a mediator of long c...

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Detalhes bibliográficos
Main Authors: Huang, Huan, McIntosh, Avery L., Martin, Gregory G., Petrescu, Anca D., Landrock, Kerstin K., Landrock, Danilo, Kier, Ann B., Schroeder, Friedhelm
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600304/
https://ncbi.nlm.nih.gov/pubmed/23533380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/865604
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