HUMAN LIVER FATTY ACID BINDING PROTEIN (L-FABP) T94A VARIANT ALTERS STRUCTURE, STABILITY, AND INTERACTION WITH FIBRATES

Although the human L-FABP T94A variant arises from the most commonly occurring SNP in the entire FABP family, there is a complete lack of understanding regarding the role of this polymorphism in human disease. It has been hypothesized that the T94A substitution results in complete loss of ligand bin...

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Hoofdauteurs: Martin, Gregory G., McIntosh, Avery L., Huang, Huan, Gupta, Shipra, Atshaves, Barbara P., Landrock, Kerstin K., Landrock, Danilo, Kier, Ann B., Schroeder, Friedhelm
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930105/
https://ncbi.nlm.nih.gov/pubmed/24299557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401014k
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