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Human FABP1 T94A variant impacts fatty acid metabolism and PPAR-α activation in cultured human female hepatocytes

Although human liver fatty acid-binding protein (FABP1) T94A variant has been associated with nonalcoholic fatty liver disease and reduced ability of fenofibrate to lower serum triglycerides (TG) to target levels, molecular events leading to this phenotype are poorly understood. Cultured primary hep...

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Detalhes bibliográficos
Main Authors: McIntosh, Avery L., Huang, Huan, Storey, Stephen M., Landrock, Kerstin K., Landrock, Danilo, Petrescu, Anca D., Gupta, Shipra, Atshaves, Barbara P., Kier, Ann B., Schroeder, Friedhelm
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101680/
https://ncbi.nlm.nih.gov/pubmed/24875102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00369.2013
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