Human FABP1 T94A variant impacts fatty acid metabolism and PPAR-α activation in cultured human female hepatocytes

Although human liver fatty acid-binding protein (FABP1) T94A variant has been associated with nonalcoholic fatty liver disease and reduced ability of fenofibrate to lower serum triglycerides (TG) to target levels, molecular events leading to this phenotype are poorly understood. Cultured primary hep...

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Main Authors: McIntosh, Avery L., Huang, Huan, Storey, Stephen M., Landrock, Kerstin K., Landrock, Danilo, Petrescu, Anca D., Gupta, Shipra, Atshaves, Barbara P., Kier, Ann B., Schroeder, Friedhelm
格式: Artigo
語言:Inglês
出版: American Physiological Society 2014
主題:
Liver and Biliary Tract
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101680/
https://ncbi.nlm.nih.gov/pubmed/24875102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00369.2013
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