Inhibitors of Fatty Acid Synthesis Induce PPARα-Regulated Fatty Acid β-Oxidative Genes: Synergistic Roles of L-FABP and Glucose

While TOFA (acetyl CoA carboxylase inhibitor) and C75 (fatty acid synthase inhibitor) prevent lipid accumulation by inhibiting fatty acid synthesis, the mechanism of action is not simply accounted for by inhibition of the enzymes alone. Liver fatty acid binding protein (L-FABP), a mediator of long c...

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Détails bibliographiques
Auteurs principaux: Huang, Huan, McIntosh, Avery L., Martin, Gregory G., Petrescu, Anca D., Landrock, Kerstin K., Landrock, Danilo, Kier, Ann B., Schroeder, Friedhelm
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600304/
https://ncbi.nlm.nih.gov/pubmed/23533380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/865604
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