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A recombinant scFv-FasL(ext) as a targeting cytotoxic agent against human Jurkat-Ras cancer

BACKGROUND: Targeted therapy of human cancers is an attractive approach and has been investigated with limited success. We have developed novel cytotoxic agents for targeted therapy of human cancers based on the extracellular cytotoxicity domain of CD178 (FasL) and the specificity offered by single...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chan, Derek V, Sharma, Rahul, Ju, Chiao-Ying A, Roffler, Steve R, Ju, Shyr-Te
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599744/
https://ncbi.nlm.nih.gov/pubmed/23497165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-16
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