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A recombinant scFv-FasL(ext) as a targeting cytotoxic agent against human Jurkat-Ras cancer

BACKGROUND: Targeted therapy of human cancers is an attractive approach and has been investigated with limited success. We have developed novel cytotoxic agents for targeted therapy of human cancers based on the extracellular cytotoxicity domain of CD178 (FasL) and the specificity offered by single...

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Detalhes bibliográficos
Main Authors: Chan, Derek V, Sharma, Rahul, Ju, Chiao-Ying A, Roffler, Steve R, Ju, Shyr-Te
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599744/
https://ncbi.nlm.nih.gov/pubmed/23497165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-16
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