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A recombinant scFv-FasL(ext) as a targeting cytotoxic agent against human Jurkat-Ras cancer
BACKGROUND: Targeted therapy of human cancers is an attractive approach and has been investigated with limited success. We have developed novel cytotoxic agents for targeted therapy of human cancers based on the extracellular cytotoxicity domain of CD178 (FasL) and the specificity offered by single...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599744/ https://ncbi.nlm.nih.gov/pubmed/23497165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-16 |
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