Automated hierarchical classification of protein domain subfamilies based on functionally-divergent residue signatures

BACKGROUND: The NCBI Conserved Domain Database (CDD) consists of a collection of multiple sequence alignments of protein domains that are at various stages of being manually curated into evolutionary hierarchies based on conserved and divergent sequence and structural features. These domain models a...

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Detaylı Bibliyografya
Asıl Yazarlar: Neuwald, Andrew F, Lanczycki, Christopher J, Marchler-Bauer, Aron
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Methodology Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599474/
https://ncbi.nlm.nih.gov/pubmed/22726767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-144
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