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Nicotine Affects Bone Resorption and Suppresses the Expression of Cathepsin K, MMP-9 and Vacuolar-Type H(+)-ATPase d2 and Actin Organization in Osteoclasts

Tobacco smoking is an important risk factor for the development of several cancers, osteoporosis, and inflammatory diseases such as periodontitis. Nicotine is one of the major components of tobacco. In previous study, we showed that nicotine inhibits mineralized nodule formation by osteoblasts, and...

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書誌詳細
主要な著者: Tanaka, Hideki, Tanabe, Natsuko, Kawato, Takayuki, Nakai, Kumiko, Kariya, Taro, Matsumoto, Sakurako, Zhao, Ning, Motohashi, Masafumi, Maeno, Masao
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598738/
https://ncbi.nlm.nih.gov/pubmed/23555029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059402
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