Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors through MAPK Signaling Pathways in MC3T3-E1 cells

Objective: Matrix metalloproteinases (MMPs), produced by osteoblasts, catalyze the turnover of extracellular matrix (ECM) molecules in osteoid, and the regulation of MMP activity depends on interactions between MMPs and tissue inhibitors of metalloproteinases (TIMPs). We focused on the degradation p...

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Dades bibliogràfiques
Publicat a:Int J Med Sci
Autors principals: Karasawa, Yoko, Tanaka, Hideki, Nakai, Kumiko, Tanabe, Natsuko, Kawato, Takayuki, Maeno, Masao, Shimizu, Noriyoshi
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643081/
https://ncbi.nlm.nih.gov/pubmed/26640410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.13263
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