Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors through MAPK Signaling Pathways in MC3T3-E1 cells

Objective: Matrix metalloproteinases (MMPs), produced by osteoblasts, catalyze the turnover of extracellular matrix (ECM) molecules in osteoid, and the regulation of MMP activity depends on interactions between MMPs and tissue inhibitors of metalloproteinases (TIMPs). We focused on the degradation p...

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Vydáno v:Int J Med Sci
Hlavní autoři: Karasawa, Yoko, Tanaka, Hideki, Nakai, Kumiko, Tanabe, Natsuko, Kawato, Takayuki, Maeno, Masao, Shimizu, Noriyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2015
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643081/
https://ncbi.nlm.nih.gov/pubmed/26640410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.13263
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