Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors through MAPK Signaling Pathways in MC3T3-E1 cells

Objective: Matrix metalloproteinases (MMPs), produced by osteoblasts, catalyze the turnover of extracellular matrix (ECM) molecules in osteoid, and the regulation of MMP activity depends on interactions between MMPs and tissue inhibitors of metalloproteinases (TIMPs). We focused on the degradation p...

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Detalles Bibliográficos
Publicado en:Int J Med Sci
Main Authors: Karasawa, Yoko, Tanaka, Hideki, Nakai, Kumiko, Tanabe, Natsuko, Kawato, Takayuki, Maeno, Masao, Shimizu, Noriyoshi
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643081/
https://ncbi.nlm.nih.gov/pubmed/26640410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.13263
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