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Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis
BACKGROUND: Group I metabotropic glutamate receptors (mGluR) are coupled via Gα(q/11) to the activation of phospholipase Cβ, which hydrolyzes membrane phospholipids to form inositol 1,4,5 trisphosphate and diacylglycerol. In addition to functioning as neurotransmitter receptors to modulate synaptic...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598502/ https://ncbi.nlm.nih.gov/pubmed/23406666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-9 |
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