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A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter.
bcl-2 mRNA is present at high levels in pre-B-cell lines but is down-regulated in most mature B-cell lines. To investigate the mechanisms responsible for its developmental control, we studied the regulation of bcl-2 expression in human B-lineage cell lines. Using nuclear run-on assays, we found that...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3686 |
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