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A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter.
bcl-2 mRNA is present at high levels in pre-B-cell lines but is down-regulated in most mature B-cell lines. To investigate the mechanisms responsible for its developmental control, we studied the regulation of bcl-2 expression in human B-lineage cell lines. Using nuclear run-on assays, we found that...
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| Опубликовано в: : | Mol Cell Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1993
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3686 |
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