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Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3′ Untranslated Region

BCL-2-related ovarian killer (BOK) is a pro-apoptotic BAX-like member of the BCL-2 family with suggested tumor suppressor activity. The molecular mechanisms regulating BOK expression are poorly understood and fail to explain a frequent lack of concordance between protein and transcript levels. Here,...

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Publicat a:iScience
Autors principals: Fernandez-Marrero, Yuniel, Bachmann, Daniel, Lauber, Emanuel, Kaufmann, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260365/
https://ncbi.nlm.nih.gov/pubmed/30471638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.11.005
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