Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

We conducted a genome-wide SNP association study on prostate cancer on over 23,000 Icelanders, followed by a replication study including over 15,500 individuals from Europe and the United States. Two newly identified variants were shown to be associated with prostate cancer: rs5945572 on Xp11.22 and...

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Main Authors: Gudmundsson, Julius, Sulem, Patrick, Rafnar, Thorunn, Bergthorsson, Jon T, Manolescu, Andrei, Gudbjartsson, Daniel, Agnarsson, Bjarni A, Sigurdsson, Asgeir, Benediktsdottir, Kristrun R, Blondal, Thorarinn, Jakobsdottir, Margret, Stacey, Simon N, Kostic, Jelena, Kristinsson, Kari T, Birgisdottir, Birgitta, Ghosh, Shyamali, Magnusdottir, Droplaug N, Thorlacius, Steinunn, Thorleifsson, Gudmar, Zheng, S Lilly, Sun, Jielin, Chang, Bao-Li, Elmore, J Bradford, Breyer, Joan P, McReynolds, Kate M, Bradley, Kevin M, Yaspan, Brian L, Wiklund, Fredrik, Stattin, Par, Lindström, Sara, Adami, Hans-Olov, McDonnell, Shannon K, Schaid, Daniel J, Cunningham, Julie M, Wang, Liang, Cerhan, James R, St Sauver, Jennifer L, Isaacs, Sara D, Wiley, Kathleen E, Partin, Alan W, Walsh, Patrick C, Polo, Sonia, Ruiz-Echarri, Manuel, Navarrete, Sebastian, Fuertes, Fernando, Saez, Berta, Godino, Javier, Weijerman, Philip C, Swinkels, Dorine W, Aben, Katja K, Witjes, J Alfred, Suarez, Brian K, Helfand, Brian T, Frigge, Michael L, Kristjansson, Kristleifur, Ober, Carole, Jonsson, Eirikur, Einarsson, Gudmundur V, Xu, Jianfeng, Gronberg, Henrik, Smith, Jeffrey R, Thibodeau, Stephen N, Isaacs, William B, Catalona, William J, Mayordomo, Jose I, Kiemeney, Lambertus A, Barkardottir, Rosa B, Gulcher, Jeffrey R, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598012/
https://ncbi.nlm.nih.gov/pubmed/18264098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.89
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