A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

Western countries, prostate cancer is the most prevalent cancer of men, and one of the leading causes of cancer-related death in men. Several genome-wide association studies have yielded numerous common variants conferring risk of prostate cancer. In the present study we analyzed 32.5 million varian...

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Main Authors: Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F., Masson, Gisli, Agnarsson, Bjarni A., Benediktsdottir, Kristrun R., Sigurdsson, Asgeir, Magnusson, Olafur Th., Gudjonsson, Sigurjon A., Magnusdottir, Droplaug N., Johannsdottir, Hrefna, Helgadottir, Hafdis Th., Stacey, Simon N., Jonasdottir, Adalbjorg, Olafsdottir, Stefania B., Thorleifsson, Gudmar, Jonasson, Jon G., Tryggvadottir, Laufey, Navarrete, Sebastian, Fuertes, Fernando, Helfand, Brian T., Hu, Qiaoyan, Csiki, Irma E., Mates, Ioan N., Jinga, Viorel, Aben, Katja K. H., van Oort, Inge M., Vermeulen, Sita H., Donovan, Jenny L., Hamdy, Freddy C., Ng, Chi-Fai, Chiu, Peter K.F., Lau, Kin-Mang, Ng, Maggie C.Y., Gulcher, Jeffrey R., Kong, Augustine, Catalona, William J., Mayordomo, Jose I., Einarsson, Gudmundur V., Barkardottir, Rosa B., Jonsson, Eirikur, Mates, Dana, Neal, David E., Kiemeney, Lambertus A., Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562711/
https://ncbi.nlm.nih.gov/pubmed/23104005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2437
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