Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

We report a genome-wide association follow up study on prostate cancer. We identify four variants associated with the disease in European populations: rs10934853-A (OR = 1.12, P = 2.9×10(−10)) on 3q21.3, two moderately correlated (r(2) = 0.07) variants on 8q24.21; rs16902094-G (OR = 1.21, P = 6.2×10...

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Huvudupphovsmän: Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F., Blondal, Thorarinn, Gylfason, Arnaldur, Agnarsson, Bjarni A., Benediktsdottir, Kristrun R., Magnusdottir, Droplaug N., Orlygsdottir, Gudbjorg, Jakobsdottir, Margret, Stacey, Simon N., Sigurdsson, Asgeir, Wahlfors, Tiina, Tammela, Teuvo, Breyer, Joan P., McReynolds, Kate M., Bradley, Kevin M., Saez, Berta, Godino, Javier, Navarrete, Sebastian, Fuertes, Fernando, Murillo, Laura, Polo, Eduardo, Aben, Katja K., van Oort, Inge M., Suarez, Brian K., Helfand, Brian T., Kan, Donghui, Zanon, Carlo, Frigge, Michael L., Kristjansson, Kristleifur, Gulcher, Jeffrey R., Einarsson, Gudmundur V., Jonsson, Eirikur, Catalona, William J., Mayordomo, Jose I., Kiemeney, Lambertus A., Smith, Jeffrey R., Schleutker, Johanna, Barkardottir, Rosa B., Kong, Augustine, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562712/
https://ncbi.nlm.nih.gov/pubmed/19767754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.448
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