Detection of sharing by descent, long-range phasing and haplotype imputation

Uncertainty about the phase of strings of single nucleotide polymorphisms (SNPs) creates complications in genetic analysis although methods have been developed for phasing population-based samples. However, these methods can only phase a small number of SNPs effectively, and become unreliable when a...

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Udgivet i:Nat Genet
Main Authors: Kong, Augustine, Masson, Gisli, Frigge, Michael L., Gylfason, Arnaldur, Zusmanovich, Pasha, Thorleifsson, Gudmar, Olason, Pall I., Ingason, Andres, Steinberg, Stacy, Rafnar, Thorunn, Sulem, Patrick, Mouy, Magali, Jonsson, Frosti, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Hreinn, Stefansson, Kari
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540081/
https://ncbi.nlm.nih.gov/pubmed/19165921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.216
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