Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation

Lumbar disc herniation (LDH) is common and often debilitating. Microdiscectomy of herniated lumbar discs (LDHsurg) is performed on the most severe cases to resolve the resulting sciatica. Here we perform a genome-wide association study on 4,748 LDHsurg cases and 282,590 population controls and disco...

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Published in:Nat Commun
Main Authors: Bjornsdottir, Gyda, Benonisdottir, Stefania, Sveinbjornsson, Gardar, Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Walters, G. Bragi, Bjornsson, Aron, Olafsson, Ingvar H., Ulfarsson, Elfar, Vikingsson, Arnor, Hansdottir, Ragnheidur, Karlsson, Karl O., Rafnar, Thorunn, Jonsdottir, Ingileif, Frigge, Michael L., Kong, Augustine, Oddsson, Asmundur, Masson, Gisli, Magnusson, Olafur T., Gudbjartsson, Tomas, Stefansson, Hreinn, Sulem, Patrick, Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Thorgeirsson, Thorgeir E., Stefansson, Kari
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322534/
https://ncbi.nlm.nih.gov/pubmed/28223688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14265
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