Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation

Lumbar disc herniation (LDH) is common and often debilitating. Microdiscectomy of herniated lumbar discs (LDHsurg) is performed on the most severe cases to resolve the resulting sciatica. Here we perform a genome-wide association study on 4,748 LDHsurg cases and 282,590 population controls and disco...

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Wydane w:Nat Commun
Główni autorzy: Bjornsdottir, Gyda, Benonisdottir, Stefania, Sveinbjornsson, Gardar, Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Walters, G. Bragi, Bjornsson, Aron, Olafsson, Ingvar H., Ulfarsson, Elfar, Vikingsson, Arnor, Hansdottir, Ragnheidur, Karlsson, Karl O., Rafnar, Thorunn, Jonsdottir, Ingileif, Frigge, Michael L., Kong, Augustine, Oddsson, Asmundur, Masson, Gisli, Magnusson, Olafur T., Gudbjartsson, Tomas, Stefansson, Hreinn, Sulem, Patrick, Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Thorgeirsson, Thorgeir E., Stefansson, Kari
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group 2017
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322534/
https://ncbi.nlm.nih.gov/pubmed/28223688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14265
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