Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction

We use polygenic risk scores (PRSs) for schizophrenia (SCZ) and bipolar disorder (BPD) to predict smoking, and addiction to nicotine, alcohol or drugs in individuals not diagnosed with psychotic disorders. Using PRSs for 144 609 subjects, including 10 036 individuals admitted for in‐patient addictio...

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Bibliografski detalji
Izdano u:Addict Biol
Glavni autori: Reginsson, Gunnar W., Ingason, Andres, Euesden, Jack, Bjornsdottir, Gyda, Olafsson, Sigurgeir, Sigurdsson, Engilbert, Oskarsson, Hogni, Tyrfingsson, Thorarinn, Runarsdottir, Valgerdur, Hansdottir, Ingunn, Steinberg, Stacy, Stefansson, Hreinn, Gudbjartsson, Daniel F., Thorgeirsson, Thorgeir E., Stefansson, Kari
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Genetic Study
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811785/
https://ncbi.nlm.nih.gov/pubmed/28231610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12496
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