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CDKN2A Mutations and Melanoma Risk in the Icelandic Population

BACKGROUND: Germline CDKN2A mutations have been observed in 20-40% of high-risk melanoma-prone families, however little is known about their prevalence in population-based series of melanoma cases and controls. METHODS: We resequenced the CDKN2A gene, including the p14ARF variant and promoter region...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Goldstein, Alisa M., Stacey, Simon N., Olafsson, Jon H., Jonsson, Gudbjörn F., Helgason, Agnar, Sulem, Patrick, Sigurgeirsson, Bardur, Benediktsdottir, Kristrun R., Thorisdottir, Kristin, Ragnarsson, Rafn, Kjartansson, Jens, Kostic, Jelena, Masson, Gisli, Kristjansson, Kristleifur, Gulcher, Jeffrey R., Kong, Augustine, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Tucker, Margaret A., Stefansson, Kari
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236640/
https://ncbi.nlm.nih.gov/pubmed/18178632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.055376
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