Cancer as a Complex Phenotype: Pattern of Cancer Distribution within and beyond the Nuclear Family

BACKGROUND: The contribution of low-penetrant susceptibility variants to cancer is not clear. With the aim of searching for genetic factors that contribute to cancer at one or more sites in the body, we have analyzed familial aggregation of cancer in extended families based on all cancer cases diagn...

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Detalhes bibliográficos
Main Authors: Amundadottir, Laufey T, Thorvaldsson, Sverrir, Gudbjartsson, Daniel F, Sulem, Patrick, Kristjansson, Kristleifur, Arnason, Sigurdur, Gulcher, Jeffrey R, Bjornsson, Johannes, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539051/
https://ncbi.nlm.nih.gov/pubmed/15630470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0010065
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