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The BARD1 Cys557Ser Variant and Breast Cancer Risk in Iceland
BACKGROUND: Most, if not all, of the cellular functions of the BRCA1 protein are mediated through heterodimeric complexes composed of BRCA1 and a related protein, BARD1. Some breast-cancer-associated BRCA1 missense mutations disrupt the function of the BRCA1/BARD1 complex. It is therefore pertinent...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479388/ https://ncbi.nlm.nih.gov/pubmed/16768547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030217 |
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