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Supervillin-mediated Suppression of p53 Protein Enhances Cell Survival

Integrin-based adhesions promote cell survival as well as cell motility and invasion. We show here that the adhesion regulatory protein supervillin increases cell survival by decreasing levels of the tumor suppressor protein p53 and downstream target genes. RNAi-mediated knockdown of a new splice fo...

詳細記述

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書誌詳細
主要な著者: Fang, Zhiyou, Luna, Elizabeth J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597829/
https://ncbi.nlm.nih.gov/pubmed/23382381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416842
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