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Supervillin-mediated Suppression of p53 Protein Enhances Cell Survival
Integrin-based adhesions promote cell survival as well as cell motility and invasion. We show here that the adhesion regulatory protein supervillin increases cell survival by decreasing levels of the tumor suppressor protein p53 and downstream target genes. RNAi-mediated knockdown of a new splice fo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597829/ https://ncbi.nlm.nih.gov/pubmed/23382381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416842 |
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