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Supervillin-mediated Suppression of p53 Protein Enhances Cell Survival

Integrin-based adhesions promote cell survival as well as cell motility and invasion. We show here that the adhesion regulatory protein supervillin increases cell survival by decreasing levels of the tumor suppressor protein p53 and downstream target genes. RNAi-mediated knockdown of a new splice fo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Fang, Zhiyou, Luna, Elizabeth J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597829/
https://ncbi.nlm.nih.gov/pubmed/23382381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416842
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