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Fucoidan Is a Novel Platelet Agonist for the C-type Lectin-like Receptor 2 (CLEC-2)

Fucoidan, a sulfated polysaccharide from Fucus vesiculosus, decreases bleeding time and clotting time in hemophilia, possibly through inhibition of tissue factor pathway inhibitor. However, its effect on platelets and the receptor by which fucoidan induces cellular processes has not been elucidated....

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Détails bibliographiques
Auteurs principaux: Manne, Bhanu Kanth, Getz, Todd M., Hughes, Craig E., Alshehri, Osama, Dangelmaier, Carol, Naik, Ulhas P., Watson, Steve P., Kunapuli, Satya P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597812/
https://ncbi.nlm.nih.gov/pubmed/23341451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424473
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