Fucoidan Is a Novel Platelet Agonist for the C-type Lectin-like Receptor 2 (CLEC-2)

Fucoidan, a sulfated polysaccharide from Fucus vesiculosus, decreases bleeding time and clotting time in hemophilia, possibly through inhibition of tissue factor pathway inhibitor. However, its effect on platelets and the receptor by which fucoidan induces cellular processes has not been elucidated....

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Autors principals: Manne, Bhanu Kanth, Getz, Todd M., Hughes, Craig E., Alshehri, Osama, Dangelmaier, Carol, Naik, Ulhas P., Watson, Steve P., Kunapuli, Satya P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597812/
https://ncbi.nlm.nih.gov/pubmed/23341451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424473
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