Fucoidan Is a Novel Platelet Agonist for the C-type Lectin-like Receptor 2 (CLEC-2)

Fucoidan, a sulfated polysaccharide from Fucus vesiculosus, decreases bleeding time and clotting time in hemophilia, possibly through inhibition of tissue factor pathway inhibitor. However, its effect on platelets and the receptor by which fucoidan induces cellular processes has not been elucidated....

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Bibliografiske detaljer
Main Authors: Manne, Bhanu Kanth, Getz, Todd M., Hughes, Craig E., Alshehri, Osama, Dangelmaier, Carol, Naik, Ulhas P., Watson, Steve P., Kunapuli, Satya P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597812/
https://ncbi.nlm.nih.gov/pubmed/23341451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424473
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