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Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Although the human mitochondrial genome has been investigated for several decades, the proteins responsible for its replication and expression, especially nucleolytic enzymes, are poorly described. Here, we characterized a novel putative PD-(D/E)XK nuclease encoded by the human C20orf72 gene named D...

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Autori principali: Szczesny, Roman J., Hejnowicz, Monika S., Steczkiewicz, Kamil, Muszewska, Anna, Borowski, Lukasz S., Ginalski, Krzysztof, Dziembowski, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597694/
https://ncbi.nlm.nih.gov/pubmed/23358826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt029
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