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Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Although the human mitochondrial genome has been investigated for several decades, the proteins responsible for its replication and expression, especially nucleolytic enzymes, are poorly described. Here, we characterized a novel putative PD-(D/E)XK nuclease encoded by the human C20orf72 gene named D...

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Detalhes bibliográficos
Main Authors: Szczesny, Roman J., Hejnowicz, Monika S., Steczkiewicz, Kamil, Muszewska, Anna, Borowski, Lukasz S., Ginalski, Krzysztof, Dziembowski, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597694/
https://ncbi.nlm.nih.gov/pubmed/23358826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt029
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