Sequence, structure and functional diversity of PD-(D/E)XK phosphodiesterase superfamily

Proteins belonging to PD-(D/E)XK phosphodiesterases constitute a functionally diverse superfamily with representatives involved in replication, restriction, DNA repair and tRNA–intron splicing. Their malfunction in humans triggers severe diseases, such as Fanconi anemia and Xeroderma pigmentosum. To...

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Main Authors: Steczkiewicz, Kamil, Muszewska, Anna, Knizewski, Lukasz, Rychlewski, Leszek, Ginalski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
Survey and Summary
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424549/
https://ncbi.nlm.nih.gov/pubmed/22638584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks382
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