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FAM46 proteins are novel eukaryotic non-canonical poly(A) polymerases

FAM46 proteins, encoded in all known animal genomes, belong to the nucleotidyltransferase (NTase) fold superfamily. All four human FAM46 paralogs (FAM46A, FAM46B, FAM46C, FAM46D) are thought to be involved in several diseases, with FAM46C reported as a causal driver of multiple myeloma; however, the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kuchta, Krzysztof, Muszewska, Anna, Knizewski, Lukasz, Steczkiewicz, Kamil, Wyrwicz, Lucjan S., Pawlowski, Krzysztof, Rychlewski, Leszek, Ginalski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857005/
https://ncbi.nlm.nih.gov/pubmed/27060136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw222
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