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Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology
Deregulation of mini-chromosome maintenance (MCM) proteins is associated with genomic instability and cancer. MCM complexes are recruited to replication origins for genome duplication. Paradoxically, MCM proteins are in excess than the number of origins and are associated with chromatin regions away...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597688/ https://ncbi.nlm.nih.gov/pubmed/23361460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt022 |
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