Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology

Deregulation of mini-chromosome maintenance (MCM) proteins is associated with genomic instability and cancer. MCM complexes are recruited to replication origins for genome duplication. Paradoxically, MCM proteins are in excess than the number of origins and are associated with chromatin regions away...

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Bibliografische gegevens
Hoofdauteurs: Slaymaker, Ian M., Fu, Yang, Toso, Daniel B., Ranatunga, Nimna, Brewster, Aaron, Forsburg, Susan L., Zhou, Z. Hong, Chen, Xiaojiang S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
Onderwerpen:
Structural Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597688/
https://ncbi.nlm.nih.gov/pubmed/23361460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt022
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